{"product_id":"sematide-inj-0-5mg-1s","title":"Sematide Injection 0.5MG (1 Box = 1 Prefilled Syringe)","description":"\u003cdiv class=\"productDescription_descriptionWrapper3___ZqGB\"\u003e\n\u003ch3 class=\"MuiTypography-root MuiTypography-body1 productDescription_productSubTitle__y_nDL css-9l3uo3\"\u003eGenerics\u003c\/h3\u003e\n\u003cp\u003eSemaglutide\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"productDescription_descriptionWrapper3___ZqGB\"\u003e\n\u003ch3 class=\"MuiTypography-root MuiTypography-body1 productDescription_productSubTitle__y_nDL css-9l3uo3\"\u003eUsed For\u003c\/h3\u003e\n\u003cp\u003eDiabetes\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"productDescription_descriptionWrapper3___ZqGB\"\u003e\n\u003ch3 class=\"MuiTypography-root MuiTypography-body1 productDescription_productSubTitle__y_nDL css-9l3uo3\"\u003eHow it works\u003c\/h3\u003e\n\u003cp\u003eSemaglutide is a GLP-1 analogue with 94% sequence homology to human GLP-1. Semaglutide acts as a GLP-1 receptor agonist that selectively binds to and activates the GLP-1 receptor, the target for native GLP-1. GLP-1 is a physiological hormone that has multiple actions on glucose, mediated by the GLP-1 receptors. The principal mechanism of protraction resulting in the long half-life of semaglutide is albumin binding, which results in decreased renal clearance and protection from metabolic degradation. Furthermore, semaglutide is stabilized against degradation by the DPP-4 enzyme. Semaglutide reduces blood glucose through a mechanism where it stimulates insulin secretion and lowers glucagon secretion, both in a glucose-dependent manner. Thus, when blood glucose is high, insulin secretion is stimulated and glucagon secretion is inhibited. The mechanism of blood glucose lowering also involves a minor delay in gastric emptying in the early postprandial phase.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Ferozsons Laboratories Limited","offers":[{"title":"1900","offer_id":47750079774956,"sku":"108590","price":1900.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0713\/3616\/5612\/files\/Untitleddesign-2026-06-16T114935.993.jpg?v=1781592601","url":"https:\/\/pillbox.pk\/ur\/products\/sematide-inj-0-5mg-1s","provider":"PILLBOX+","version":"1.0","type":"link"}