It is indicated in duodenal ulcer (a sore on the first part of the small intestine), benign (non-cancerous) gastric ulcers (sores on stomach lining), for prevention of NSAID induced inflammation, Zollinger-Ellison syndrome (rare digestive disorder that results in excessive gastric acid), prevention and treatment of gastroesophageal reflux disease (a disorder that causes the digestive juices, foods or fluids back up from the stomach into the esophagus). It is also used with antibiotics for the eradication of Helicobacter Pylori in patients with duodenal ulcer (a sore on the first part of the small intestine) or gastritis (inflammation of stomach cells).