Generics
Cinitapride
Used For
Gastroesophageal Reflux Disease
How it works
Cinitapride is an orthopramide with gastrointestinal prokinetic activity, with considerable muscarinic properties. It blocks the presynaptic serotonin receptors and increases its release, resulting in greater serotonergic activity. Though it has discrete antidopaminergic activity, this adds to cinitapride’s therapeutic effect. Cinitapride efficacy could be due not only to an increase in the pressure of the inferior oesophageal sphincter but also due to its prokinetic effect.