Ezetimibe Used For Cholesterol Control

How it works

Ezetimibe decreases blood cholesterol by inhibiting the absorption of cholesterol by the small intestine. Unlike other cholesterol-lowering compounds, ezetimibe does not inhibit cholesterol synthesis in the liver nor does it increase bile acid excretion. Ezetimibe acts at the brush border of the small intestine to inhibit the absorption of cholesterol leading to a reduction in the amount of cholesterol delivered to the liver. This in turn causes a reduction of hepatic cholesterol stores and an increase in cholesterol clearance from the blood.