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Diclofenac potassium is a topical agent used for relieving joint pain in patients with arthritis. It is a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain associated with arthritis. It achieves this by inhibiting the body's production of chemicals that stimulate inflammation and blood clotting. Diclofenac potassium is also described as potassium salt of diclofenac, a member of the phenylacetic acid class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is widely used in managing painful inflammatory conditions such as osteoarthritis and rheumatoid arthritis, thanks to its potent anti-inflammatory and analgesic properties. Topical diclofenac works by blocking enzymes called cyclooxygenases (COX-1 and COX-2) that are involved in the conversion of prostaglandin H2 (PGH2) to other prostaglandins (PGE2, PGF2alpha, and PGD2). These prostaglandins are released during inflammation and have been implicated in dysregulation of the inflammatory response. By blocking their production, diclofenac potently reduces inflammation and pain. Arthritis is a common disorder characterized by painful inflammation of the joints, and diclofenac Potassium 50mg is often used as a safe and effective way to relieve arthritis-related pain and inflammation.