Amantadine Sulphate Used For Anti-Parkinson

How it works

Amantadine Sulphate is (I-aminoadamantan) a tricyclic, symmeteric amine with an antiviral activity against RNA & DNA viruses. Although exact mode of action of amantadine is not well understood, antiviral activity was found to be related to inhibition of viral uncoating and viral budding by interaction with the viral M2 protein which is a membrane protein. It has established role in influenza and is also used in Parkinson’s disease as an effective therapeutic agent having antagonistic action on NMDA-ion a channel in basal ganglia which comprehensively improves the troublesome symptom of rigidity, tremor and hypokinesia, particularly the psychic brightening and the increased interest in surrounding.